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Tara Moore uploaded papers on Academia.edu.
Staphylococcus aureus Activates the NLRP3 Inflammasome in Human and Rat Conjunctival Goblet Cells
by Tara Moore
The conjunctiva is a moist mucosal membrane that is constantly exposed to an array of potential pathogens and triggers of inflammation. The NACHT, leucine rich repeat (LRR), and pyrin domain-containing protein 3 (NLRP3) is a Nod-like receptor that can sense pathogens or other triggers, and is hig...
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Small optical zones with aspheric profiles in laser refractive surgery for myopia: A surgical outcome and patient satisfaction study
by Tara Moore
Purpose: To assess the outcomes of small optical zone (OZ) ablations used in conjunction with large transition zones (TZ) and a highly aspheric treatment profile. Methods: Interventional case series of 39 consecutive patients with myopia or myopic astigmatism. Patient data included pre and postop...
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Methadone, codeine and acute haemorrhagic necrotising pancreatitis: Which came first?
by Tara Moore
Acute haemorrhagic necrotising pancreatitis lead to the death at home of a young female who was on a methadone maintenance programme. Toxic levels of codeine with potentially lethal levels of methadone and morphine were found at post-mortem. Whether opiates caused the pancreatitis or were the con...
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IFNc expression by an attenuated strain of Salmonella enterica serovar Typhimurium improves vaccine efficacy in susceptible TLR4-defective C3H/HeJ mice
by Tara Moore
C3H/HeJ mice carry a mutated allele of TLR4 gene (TLR4d) and thus are hyporesponsive to the lethal effects of lipopolysaccharide (LPS). Characteristically, however, the mice are also hypersusceptible to infections, particularly by Gram-negative bacteria such as Salmonella enterica serovar Typhimu...
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Is there a role for ethanol assay using alcohol dehydrogenase in a basic drugs and alcohol screen of blood following routine autopsies
by Tara Moore
The external examination system of determining the cause of death as operated in Dundee, Scotland is controversial. The addition of a blood or urine specimen for drugs and alcohol processed by hospital autoanalysers will reduce error in death certification. This is even more convenient to organis...
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Biochemical toxicology and suicide in Ireland: a laboratory study
by Tara Moore
Background Biochemical toxicology in suicides provides a template to improve preventive interventions in cases of suicide. The menu for biochemical toxicological analysis in coroners' cases is not prescriptive in Ireland or in the United Kingdom. The aim of the study was to confirm that reliance ...
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Ethanol as a single toxin in non-traumatic deaths – A toxicology perspective
by Tara Moore
There were 285 autopsy cases in 2010 where ethanol was the only toxin. To try to ascertain the toxicity of ethanol alone, those cases where clinical details stated 'sudden death', 'collapsed', 'brought in dead to hospital', 'found dead at home', 'fell down stairs and dead at end of stairs', 'sudd...
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Poisonings and clinical toxicology: a template for Ireland
by Tara Moore
Background Poisons information is accessed around the clock in the British Isles from six centres of which two are in Ireland at Dublin and Belfast accompanied by consultant toxicologist advisory service. The numbers of calls in Ireland are down to about 40 per day due to easy access to online da...
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Diabetes diagnosis and autopsy
by Tara Moore
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Clinical Study Near Visual Acuity Following Hyperopic Photorefractive Keratectomy in a Presbyopic Age Group
by Tara Moore
Purpose. To assess near visual acuity in a presbyopic age group following hyperopic photorefractive keratectomy (PRK). Setting. Private practice in Siena, Italy. Methods. In this retrospective single-surgeon comparative study, PRK with mitomycin C was performed to correct hyperopia using Bausch &...
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